No imaging technology can achieve infinite resolution. For over 150 years, scientists have understood that regardless of how advanced a microscope or camera may be, there is a fundamental limit to its resolution. This limit stems not from technological shortcomings, but from the inherent nature of light and the fundamental rules of information transmission.
A global research team led by the Vienna University of Technology (TU Wien) in Austria has investigated a central question: What is the ultimate precision limit of optical methods—and how close can we get to it? The team not only calculated the theoretical limit of optical measurement precision, but also developed an AI algorithm based on neural networks capable of approaching that limit with remarkable accuracy after training.
The researchers tested their approach under complex imaging conditions, such as when light passes through scattering media like biological tissue or frosted glass. In these cases, object location information becomes highly distorted, forming seemingly random light patterns. Traditional methods struggle to recover useful data, but AI has shown extraordinary potential. By training the neural network on large datasets of known object positions and corresponding light patterns, the system learned to accurately infer the position of new objects based on incoming images.
The key breakthrough lies in the AI's predictive performance, which comes astonishingly close to the theoretical limit determined by Fisher Information—a metric that defines the maximum amount of information extractable from a signal. Experimental results show that the AI's performance differs only marginally from this theoretical optimum, indicating it is nearing the highest precision allowed by the laws of physics.
This research opens up wide-ranging possibilities for real-world applications in fields such as medical imaging, materials science, and quantum technology. Moving forward, the team plans to collaborate with experts in medicine and engineering to bring this breakthrough into practical use.